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Reduction of fluid creep in the ICU: Max Concentration of Levophed infusions of > 15 mcg/min

Grace DeMarco, Anna Elise Scott, Dr. Jack DePriest 

ICU patients frequently require continuous medications via fluid drip, which can lead to volume overload over the course of hospitalization, a phenomenon called ‘fluid creep.’ This slow increase in fluid, and ultimately, volume overload, can result in increased morbidity and mortality in critically ill patients. By focusing on Levophed (Norepinephrine), a common pressor medication utilized in the ICU, our goal was to reduce the total volume administered by max concentrating the fluids earlier in the hospital course. For patients receiving a dose of > 15mcg/min of Levophed, our plan was to implement a protocol in which the fluids were max concentrated by hour two of delivery. This project is ongoing, and no data has been collected at this point. 

© 2020 by The UofSC SOM Research Center for Transforming Health

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